Sektionen

Publikationen 2018

Publikationen 2018

  1. Alsat EA, Reutter H, Bagci S, Kipfmueller F, Engels H, Raff R, Mangold E, Gembruch U, Geipel A, Müller A, Schaible T (2018) Congenital diaphragmatic hernia in a case of Cat eye syndrome. Clinical Case Reports 6:1786-1790. PMID: 30214764

  2. Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Yin D, Ellis G, Ben-Shoshan M, Marenholz I, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk R, Dubois AEJ, Grosche S, Ashley S, Rüschendorf F, Kalb B, Beyer K, Nöthen MM, Lee YA, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D (2018) A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma. Journal of Allergy and Clinical Immunology 141:1513-1516. PMID: 29325868

  3. Bagci S, Mensinga D, Katzer D, Merz WM, Reutter H, Müller A (2018) An examination of the factors affecting intestinal wall integrity in newborns at birth. Journal of Maternal-Fetal & Neonatal Medicine 31:294-299. PMID: 28110600

  4. Begemann M, Rezwan FI, Beygo J, Docherty LE, Kolarova J, Schroeder C, Buiting K, Chokkalingam K, Degenhardt F, Wakeling EL, Kleinle S, González Fassrainer D, Oehl-Jaschkowitz B, Turner CLS, Patalan M, Gizewska M, Binder G, Bich Ngoc CT, Chi Dung V, Mehta SG, Baynam G, Hamilton-Shield JP, Aljareh S, Lokulo-Sodipe O, Horton R, Siebert R, Elbracht M, Temple IK, Eggermann T, Mackay DJG (2018) Maternal variants in NLRP and other maternal effect proteins are associated with multilocus imprinting disturbance in offspring. Journal of Medical Genetics 55:497-504. PMID: 29574422

  5. Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Herms F, Hoffmann P, Nöthen MM, Reif A] (2018) Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell 173(7):1705-1715. PMID: 29906448

  6. Birtel J, Eisenberger T, Gliem M, Müller PL, Herrmann P, Betz C, Zahnleiter D, Neuhaus C, Lenzner S, Holz FG, Mangold E, Bolz HJ, Charbel Issa P (2018) Clinical and genetic characteristics of 251 consecutive patients with macular and cone/cone-rod dystrophy. Science Report 19;8(1):4824. doi: 10.1038/s41598-018-22096-0. PMID: 29555955

  7. Birtel J, Gliem M, Mangold E, Müller PL, Holz FG, Neuhaus C, Lenzner S, Zahnleiter D, Betz C, Eisenberger T, Bolz HJ, Charbel Issa P (2018) Next-generation sequencing identifies unexpected genotype-phenotype correlations in patients with retinitis pigmentosa. PLoS One 13(12):e0207958. doi: 10.1371/journal.pone.0207958. eCollection 2018.PMID: 30543658

  8. Böhmer AC, Gölz L, Kreusch T, Kramer FJ, Pötzsch B, Nöthen MM, Jäger A, Mangold E, Knapp M, Ludwig KU (2018) Investigation of dominant and recessive inheritance models in genome-wide association studies data of nonsyndromic cleft lip with or without cleft palate. Birth Defects Research 110:336-341. PMID: 29134786

  9. Bogs T, Zwink N, Chonitzki V, Hölscher A, Boemers TM, Münsterer O, Kurz R, Heydweiller A, Pauly M, Leutner A, Ure BM, Lacher M, Deffaa OJ, Thiele H, Bagci S, Jenetzky E, Schumacher J, Reutter H (2018) Esophageal atresia with or without tracheoesophageal fistula (EA/TEF): Association of different EA/TEF subtypes with specific co-occurring congenital anomalies and implications for diagnostic workup. European Journal of Pediatric Surgery 28:176-182. PMID: 28061520

  10. Božić T, Frobel J, Raic A, Ticconi F, Kuo CC, Heilmann-Heimbach S, Goecke TW, Zenke M, Jost E, Costa IG, Wagner W (2018) Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis. Life Science Alliance 1(6):e201800153. doi: 10.26508/lsa.201800153. PMID: 30582132

  11. Brainstorm Consortium [Nöthen MM, Hoffmann P, Herms S, Maaser A, Forstner AJ, Degenhardt F, Schumacher J] (2018) Analysis of shared heritability in common disorders of the brain. Science 360 (6395). pii: eaap8757. doi: 10.1126/science.aap8757. PMID: 29930110

  12. Bramswig NC, Bertoli-Avella AM, Albrecht B, Al Aqeel AI, Alhashem A, Al-Sannaa N, Bah M, Bröhl K, Depienne C, Dorison N, Doummar D, Ehmke N, Elbendary HM, Gorokhova S, Héron D, Horn D, James K, Keren B, Kuechler A, Ismail S, Issa MY, Marey I, Mayer M, McEvoy-Venneri J, Megarbane A, Mignot C, Mohamed S, Nava C, Philip N, Ravix C, Rolfs A, Sadek AA, Segebrecht L, Stanley V, Trautman C, Valence S, Villard L, Wieland T, Engels H, Strom TM, Zaki MS, Gleeson JG, Lüdecke HJ, Bauer P, Wieczorek D (2018) Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies). Human Genetics 137:753-768. PMID: 30167850

  13. Breuer R*, Mattheisen M*, Frank J, Krumm B, Treutlein J, Kassem L, Strohmaier J, Herms S, Mühleisen TW, Degenhardt F, Cichon S, Nöthen MM, Karypis G, Kelsoe J, Greenwood T, Nievergelt C, Shilling P, Shekhtman T, Edenberg H, Craig D, Szelinger S, Nurnberger J, Gershon E, Alliey-Rodriguez N, Zandi P, Goes F, Schork N, Smith E, Koller D, Zhang P, Badner J, Berrettini W, Bloss C, Byerley W, Coryell W, Foroud T, Guo Y, Hipolito M, Keating B, Lawson W, Liu C, Mahon P, McInnis M, Murray S, Nwulia E, Potash J, Rice J, Scheftner W, Zöllner S, McMahon FJ, Rietschel M, Schulze TG (2018) Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics. International Journal of Bipolar Disorders 6:24. doi: 10.1186/s40345-018-0132-x. PMID: 30415424 *These authors contributed equally to this work.

  14. Cao H, Harneit A, Walter H, Erk S, Braun U, Moessnang C, Geiger LS, Zang Z, Mohnke S, Heinz A, Romanczuk-Seiferth N, Mühleisen T, Mattheisen M, Witt SH, Cichon S, Nöthen MM, Rietschel M, Meyer-Lindenberg A, Tost H (2018) The 5-HTTLPR polymorphism affects network-based functional connectivity in the visual-limbic system in healthy adults. Neuropsychopharmacology 43:406-414. PMID: 28589968

  15. Casper M, Spier I, Holz R, Aretz S, Lammert F (2018) Phenotypic variability of MUTYH-associated polyposis in monozygotic twins and endoscopic resection of a giant polyp in pregnancy. American Journal of Gastroenterology 113:625-627. PMID: 29610499

  16. Chang H, Hoshina N, Zhang C, Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Landén M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, Nöthen MM; Swedish Bipolar Study Group; MooDS Bipolar Consortium, Walter H, Erk S, Heinz A, Amin N, van Duijn CM, Meyer-Lindenberg A, Tost H, Xiao X, Yamamoto T, Rietschel M, Li M (2018) The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Molecular Psychiatry 23:400-412. PMID: 28070120

  17. Chattopadhyay S, Thomsen H, da Silva Filho MI, Weinhold N, Hoffmann P, Nöthen MM, Marina A, Jöckel KH, Schmidt B, Pechlivanis S, Langer C, Goldschmidt H, Hemminki K, Försti A (2018) Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study. Molecular Medicine 24(1):30. doi: 10.1186/s10020-018-0031-8. PMID: 30134812

  18. Cheesman R, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Purves KL, Pingault JB, Breen G, Rijsdij K F, Plomin R, Eley TC (2018) Extracting stability increases the SNP heritability of emotional problems in young people. Translational Psychiatry 8:223. doi: 10.1038/s41398-018-0269-5. PMID: 30333497

  19. Chiocchetti AG, Yousaf A, Bour HS, Haslinger D, Waltes R, Duketis E, Jarczok T, Sachse M, Biscaldi M, Degenhardt F, Herms S, Cichon S, Ackermann J, Koch I, Klauck SM, Freitag CM (2018) Common functional variants of the glutamatergic system in autism spectrum disorder with high and low intellectual abilities. Journal of Neural Transmission (Vienna) 125:259-271. PMID: 29147782

  20. Claus EB, Cornish AJ, Broderick P, Schildkraut JM, Dobbins SE, Holroyd A, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Swerdlow A, Larsen SB, Johansen C, Simon M, Bondy M, Wrensch M, Houlston RS, Wiemels JL (2018) Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. Neuro-Oncology 20:1485-1493. PMID: 29762745

  21. Colodro-Conde L, Couvy-Duchesne B, Zhu G, Coventry WL, Byrne EM, Gordon S, Wright MJ, Montgomery GW, Madden PAF; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Ripke S, Eaves LJ, Heath AC, Wray NR, Medland SE, Martin NG (2018) A direct test of the diathesis-stress model for depression (2018) Molecular Psychiatry 23:1590-1596. PMID: 28696435

  22. Crawford B, Craig Z, Mansell G, White I, Smith A, Spaull S, Imm J, Hannon E, Wood A, Yaghootkar H, Ji YJ, Major Depressive Disorder Working[Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Mullins N, Lewis CM, Mill J, Murphy TM (2018) DNA methylation and inflammation marker profiles associated with a history of depression. Human Molecular Genetics 27: 2840-2850

  23. Czauderna C, Palestino-Dominguez M, Castven D, Becker D, Zanon-Rodriguez L, Hajduk J, Mahn FL, Herr M, Strand D, Strand S, Heilmann-Heimbach S, Gomez-Quiroz LE, Wörns MA, Galle PR, Marquardt JU (2018) Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver. PLoS One 13(12):e0209067. doi: 10.1371/journal.pone.0209067. PMID: 30576355

  24. Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, …, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, …, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ (2018) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications 9(1):2098. doi: 10.1038/s41467-018-04362-x. PMID: 29844566

  25. de Jong S, Diniz MJA, Saloma A, Gadelha A, Santoro ML, Ota VK, Noto C; Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Curtis C, Newhouse SJ, Patel H, Hall LS, O Reilly PF, Belangero SI, Bressan RA, Breen G (2018) Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology 1:163. doi: 10.1038/s42003-018-0155-y. eCollection 2018. PMID: 30320231

  26. Disney-Hogg L, Cornish AJ, Sud A, Law PJ, Kinnersley B, Jacobs DI, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS (2018) Impact of atopy on risk of glioma: a Mendelian randomisation study. BMC Medicine 16(1):42. doi: 10.1186/s12916-018-1027-5. PMID: 29540232

  27. Disney-Hogg L, Sud A, Law PJ, Cornish AJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Swerdlow AJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS (2018) Influence of obesity-related risk factors in the aetiology of glioma. British Journal of Cancer 118:1020-1027. PMID: 29531326

  28. Dworschak GC, Engels H, Becker J, Soellner L, Eggermann T, Kipfmueller F, Müller A, Reutter H, Kreiß M (2018) De novo duplication of 11p15 associated with congenital diaphragmatic hernia. Frontiers in Pediatrics 6:116. doi: 10.3389/fped.2018.00116. eCollection 2018. PMID: 29922638

  29. Ebert AK, Zwink N, Schwarzer N, Brunner L, Reutter H, Jenetzky E, Huber J, Ludwikowski B (2018) Needs assessment in care of adults with anorectal malformations and exstrophy-epispadias complex in Germany. Frontiers in Pediatrics 6:392. doi: 10.3389/fped.2018.00392. eCollection 2018. PMID: 30619788

  30. Engel C, Vasen HF, Seppälä T, Aretz S, Bigirwamungu-Bargeman M, de Boer SY, Bucksch K, Büttner R, Holinski-Feder E, Holzapfel S, Hüneburg R, Jacobs MAJM, Järvinen H, Kloor M, von Knebel Doeberitz M, Koornstra JJ, van Kouwen M, Langers AM, van de Meeberg PC, Morak M, Möslein G, Nagengast FM, Pylvänäinen K, Rahner N, Renkonen-Sinisalo L, Sanduleanu S, Schackert HK, Schmiegel W, Schulmann K, Steinke-Lange V, Strassburg CP, Vecht J, Verhulst ML, de Vos Tot Nederveen Cappel W, Zachariae S, Mecklin JP, Loeffler M; German HNPCC Consortium, the Dutch Lynch Syndrome Collaborative Group, and the Finnish Lynch Syndrome Registry (2018) No difference in colorectal cancer incidence or stage at detection by colonoscopy among 3 countries with different Lynch syndrome surveillance policies. Gastroenterology 155:1400-1409. PMID: 30063918

  31. Espinosa A, Hernández-Olasagarre B, Moreno-Grau S, Kleineidam L, Heilmann-Heimbach S, Hernández I, Wolfsgruber S, Wagner H, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Rodríguez-Gómez O, Abdelnour C, Gil S, Marquié M, Santos-Santos MA, Sanabria Á, Ortega G, Monté-Rubio G, Pérez A, Ibarria M, Ruiz S, Kornhuber J, Peters O, Frölich L, Hüll M, Wiltfang J, Luck T, Riedel-Heller S, Montrreal L, Cañabate P, Moreno M, Preckler S, Aguilera N, de Rojas I, Orellana A, Alegret M, Valero S, Nöthen MM, Wagner M, Jessen F, Tárraga L, Boada M, Ramírez A, Ruiz A (2018) Exploring genetic associations of Alzheimer's disease loci with mild cognitive impairment neurocognitive endophenotypes. Frontiers in Aging Neuroscience 10:340. doi: 10.3389/fnagi.2018.00340. eCollection 2018. PMID: 30425636

  32. Fernandez-Rebollo E, Eipel M, Seefried L, Hoffmann P, Strathmann K, Jakob F, Wagner W (2018) Primary osteoporosis is not reflected by disease-specific DNA methylation or accelerated epigenetic age in blood. Journal of Bone and Mineral Research 33:356-361. PMID: 28926142

  33. Foo JC, Streit F, Treutlein J, Ripke S, Witt SH, Strohmaier J, Degenhardt F, Forstner AJ, Hoffmann P, Soyka M, Dahmen N, Scherbaum N, Wodarz N, Heilmann-Heimbach S, Herms S, Cichon S, Preuss U, Gaebel W, Ridinger M, Hoffmann S, Schulze TG, Maier W, Zill P, Müller-Myhsok B, Ising M, Lucae S, Nöthen MM, Mann K, Kiefer F, Rietschel M, Frank J; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM] (2018) Shared genetic etiology between alcohol dependence and major depressive disorder. Psychiatric Genetics 28:66-70. PMID: 29901528

  34. Frank J, Ralser DJ, Betz RC (2018) Intra- and interfamilial phenotype variability associated with mutations in γ-secretase subunit-encoding PSENEN. Journal of Investigative Dermatology 138:1215-1218. PMID: 29138052

  35. Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M (2018) Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain 141:1186-1200. PMID: 29462334

  36. Freytag V, Vukojevic V, Wagner-Thelen H, Milnik A, Vogler C, Leber M, Weinhold L, Böhmer AC, Riedel-Heller S, Maier W, de Quervain DJ, Ramirez A, Papassotiropoulos A (2018) Genetic estimators of DNA methylation provide insights into the molecular basis of polygenic traits. Translational Psychiatry 2018 Jan 31;8(1):31. doi: 10.1038/s41398-017-0070-x. PMID: 29382824

  37. Fritzen D*, Kuechler A*, Grimmel M*, Becker J, Peters S, Sturm M, Hundertmark H, Schmidt A, Kreiß M, Strom TM, Wieczorek D, Haack TB, Beck-Wödl S, Cremer K**, Engels H** (2018) De novo FBXO11 mutations are associated with intellectual disability and behavioural anomalies. Human Genetics 137:401-411. PMID: 29796876. *These authors contributed equally to this work. **These authors contributed equally to this work.

  38. Gatzweiler E, Hoppe B, Dewald O, Berg C, Müller A, Reutter H, Kipfmueller F (2018) Extracorporeal membrane oxygenation support in a newborn with lower urinary tract obstruction and pulmonary hypoplasia: a case report. Journal of Medical Case Reports 12(1):210. doi: 10.1186/s13256-018-1749-1. PMID: 30012211

  39. Guzman-Parra J, Rivas F, Strohmaier J, Forstner A, Streit F, Auburger G, Propping P, Orozco-Diaz G, González MJ, Gil-Flores S, Cabaleiro-Fabeiro FJ, Del Río-Noriega F, Perez-Perez F, Haro-González J, de Diego-Otero Y, Romero-Sanchiz P, Moreno-Küstner B, Cichon S, Nöthen MM, Rietschel M, Mayoral F (2018) The Andalusian bipolar family (ABiF) study: Protocol and sample description. Revista de Psiquiatría y Salud Mental 11:199-207. PMID: 28619597

  40. Haenisch B, Molderings GJ (2018) White matter abnormalities are also repeatedly present in patients with systemic mast cell activation syndrome. Translational Psychiatry 8:95. doi: 10.1038/s41398-018-0143-5. PMID: 29743606

  41. Hall LS, Adams MJ, Arnau-Soler A, Clarke TK, Howard DM, Zeng Y, Davies G, Hagenaars SP, Maria Fernandez-Pujals A, Gibson J, Wigmore EM, Boutin TS, Hayward C, Scotland G; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Degenhardt F, Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM], Porteous DJ, Deary IJ, Thomson PA, Haley CS, McIntosh AM (2018) Genome-wide meta-analyses of stratified depression in generation Scotland and UK biobank. Translational Psychiatry 8:9. doi: 10.1038/s41398-017-0034-1. PMID: 29317602

  42. Heinrichs SKM, Hess T, Becker J, Hamann L, Vashist YK, Butterbach K, Schmidt T, Alakus H, Krasniuk I, Höblinger A, Lingohr P, Ludwig M, Hagel AF, Schildberg CW, Veits L, Gyvyte U, Weise K, Schüller V, Böhmer AC, Schröder J, Gehlen J, Kreuser N, Hofer S, Lang H, Lordick F, Malfertheiner P, Moehler M, Pech O, Vassos N, Rodermann E, Izbicki JR, Kruschewski M, Ott K, Schumann RR, Vieth M, Mangold E, Gasenko E, Kupcinskas L, Brenner H, Grimminger P, Bujanda L, Sopeña F, Espinel J, Thomson C, Pérez-Aísa Á, Campo R, Geijo F, Collette D, Bruns C, Messerle K, Gockel I, Nöthen MM, Lippert H, Ridwelski K, Lanas A, Keller G, Knapp M, Leja M, Kupcinskas J, García-González MA, Venerito M, Schumacher J (2018) Evidence for PTGER4, PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level. Cancer Medicine 7:5057-5065. PMID: 30191681

  43. Hench J, Bihl M, Bratic Hench I, Hoffmann P, Tolnay M, Bösch Al Jadooa N, Mariani L, Capper D, Frank S (2018) Satisfying your neuro-oncologist: a fast approach to routine molecular glioma diagnostics. Neuro-Oncology 20:1682-1683. PMID: 30169880

  44. Herrera-Rivero M, Zhang R, Heilmann-Heimbach S, Mueller A, Bagci S, Dresbach T, Schröder L, Holdenrieder S, Reutter HM, Kipfmueller F (2018) Circulating microRNAs are associated with pulmonary hypertension and development of chronic lung disease in congenital diaphragmatic hernia. Scientific Reports 8(1):10735. doi: 10.1038/s41598-018-29153-8. PMID: 30013141

  45. Howe LJ, Lee MK, Sharp GC, Davey Smith G, St Pourcain B, Shaffer JR, Ludwig KU, Mangold E, Marazita ML, Feingold E, Zhurov A, Stergiakouli E, Sandy J, Richmond S, Weinberg SM, Hemani G, Lewis SJ (2018) Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology. PLoS Genetics 14:e1007501. doi: 10.1371/journal.pgen.1007501. eCollection 2018 Aug. PMID: 30067744

  46. Huckins LM, Hatzikotoulas K, Southam L, Thornton LM, Steinberg J, Aguilera-McKay F, Treasure J, Schmidt U, Gunasinghe C, Romero A, Curtis C, Rhodes D, Moens J, Kalsi G, Dempster D, Leung R, Keohane A, Burghardt R, Ehrlich S, Hebebrand J, Hinney A, Ludolph A, Walton E, Deloukas P, Hofman A, Palotie A, Palta P, van Rooij FJA, Stirrups K, Adan R, Boni C, Cone R, Dedoussis G, van Furth E, Gonidakis F, Gorwood P, Hudson J, Kaprio J, Kas M, Keski-Rahonen A, Kiezebrink K, Knudsen GP, Slof-Op 't Landt MCT, Maj M, Monteleone AM, Monteleone P, Raevuori AH, Reichborn-Kjennerud T, Tozzi F, Tsitsika A, van Elburg A; Eating Disorder Working Group of the Psychiatric Genomics Consortium [Cichon S], Collier DA, Sullivan PF, Breen G, Bulik CM, Zeggini E (2018) Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Molecular Psychiatry 23:1169-1180. Erratum in: Mol Psychiatry. 2018 Sep;23(9):1. PMID: 29155802

  47. Hughes T, Sønderby IE, Polushina T, Hansson L, Holmgren A, Athanasiu L, Melbø-Jørgensen C, Hassani S, Hoeffding LK, Herms S, Bergen SE, Karlsson R, Song J, Rietschel M, Nöthen MM, Forstner AJ, Hoffmann P, Hultman CM, Landén M, Cichon S, Werge T, Andreassen OA, Le Hellard S, Djurovic S (2018) Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder. Translational Psychiatry 2018 Oct 8;8(1):210. doi: 10.1038/s41398-018-0175-x. PMID: 30297702

  48. Humbatova A, Maroofian R, Romano MT, Tafazzoli A, Behnam M, Dilaver N, Nouri N, Salehi M, Wolf S, Frank J, Kokordelis P, Betz RC (2018) An insertion mutation in HOXC13 underlies pure hair and nail ectodermal dysplasia with lacrimal duct obstruction. British Journal of Dermatology 178:e265-e267. PMID: 29278420

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  78. Peloso GM, van der Lee SJ; International Genomics of Alzheimer's Project (IGAP) [Heilmann-Heimbach S, Hoffmann, P, Nöthen MM, Forstner AJ], Destefano AL, Seshardi S (2018) Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease. Alzheimer’s & Dementia 10:595-598. PMID: 30422133

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  83. Reinbold CS*, Forstner AJ*, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Marie-Claire C, Cervantes P, Chen GB, Chen HC, Chillotti C, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dayer A, Étain B, Falkai P, Frisén L, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Jamain S, Jiménez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Lackner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, López Jaramillo CA, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Ösby U, Ozaki N, Perlis RH, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemüller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm TJ, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt SH, Wright AJ, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus E, Novák T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, McMahon FJ, Schulze TG, Rietschel M, Nöthen MM, Cichon S (2018) Analysis of the influence of microRNAs in lithium response in bipolar disorder. Frontiers in Psychiatry 9:207. doi: 10.3389/fpsyt.2018.00207. PMID: 29904359. *These authors have contributed equally to this work.

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  87. Streit F, Treutlein J, Frischknecht U, Hermann D, Mann K, Kiefer F, Sack M, Hall ASM, Frank J, Witt SH, Foo JC, Degenhardt F, Heilmann-Heimbach S, Nöthen MM, Sommer WH, Spanagel R, Rietschel M, Ende G (2018) Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes. Psychiatric Genetics 28:94-95. PMID: 29985185

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  90. Takahashi H, Cornish AJ, Sud A, Law PJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Ll'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Turnbull C, Houlston RS (2018) Mendelian randomisation study of the relationship between vitamin D and risk of glioma. Scientific Reports 8(1):2339. doi: 10.1038/s41598-018-20844-w. PMID: 29402980

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  93. Trautmann N, Foo JC, Frank J, Witt SH, Streit F, Treutlein J, von Heydendorff SC, Gilles M, Forstner AJ, Ebner-Priemer U, Nöthen MM, Deuschle M, Rietschel M, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium Consortium [Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM, Maaser A, Schumacher J, Reif A] (2018)Response to therapeutic sleep deprivation: a naturalistic study of clinical and genetic factors and post-treatment depressive symptom trajectory. Neuropsychopharmacology 43:2572-2577. PMID: 29872112

  94. van der Lee SJ, Teunissen CE, Pool R, Shipley MJ, Teumer A, Chouraki V, Melo van Lent D, Tynkkynen J, Fischer K, Hernesniemi J, Haller T, Singh-Manoux A, Verhoeven A, Willemsen G, de Leeuw FA, Wagner H, van Dongen J, Hertel J, Budde K, Willems van Dijk K, Weinhold L, Ikram MA, Pietzner M, Perola M, Wagner M, Friedrich N, Slagboom PE, Scheltens P, Yang Q, Gertzen RE, Egert S, Li S, Hankemeier T, van Beijsterveldt CEM, Vasan RS, Maier W, Peeters CFW, Jörgen Grabe H, Ramirez A, Seshadri S, Metspalu A, Kivimäki M, Salomaa V, Demirkan A, Boomsma DI, van der Flier WM, Amin N, van Duijn CM (2018) Circulating metabolites and general cognitive ability and dementia: evidence from 11 cohort studies. Alzheimer‘s & Dementia 14:707-722. PMID: 29316447

  95. van der Ven AT, Connaughton DM, Ityel H, Mann N, Nakayama M, Chen J, Vivante A, Hwang DY, Schulz J, Braun DA, Schmidt JM, Schapiro D, Schneider R, Warejko JK, Daga A, Majmundar AJ, Tan W, Jobst-Schwan T, Hermle T, Widmeier E, Ashraf S, Amar A, Hoogstraaten CA, Hugo H, Kitzler TM, Kause F, Kolvenbach CM, Dai R, Spaneas L, Amann K, Stein DR, Baum MA, Somers MJG, Rodig NM, Ferguson MA, Traum AZ, Daouk GH, Bogdanović R, Stajić N, Soliman NA, Kari JA, El Desoky S, Fathy HM, Milosevic D, Al-Saffar M, Awad HS, Eid LA, Selvin A, Senguttuvan P, Sanna-Cherchi S, Rehm HL, MacArthur DG, Lek M, Laricchia KM, Wilson MW, Mane SM, Lifton RP, Lee RS, Bauer SB, Lu W, Reutter HM, Tasic V, Shril S, Hildebrandt F (2018) Whole-exome sequencing identifies causative mutations in families with congenital anomalies of the kidney and urinary tract. Journal of the American Society of Nephrology 29:2348-2361. PMID: 30143558

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  98. Vogel BO, Lett TA, Erk S, Mohnke S, Wackerhagen C, Brandl EJ, Romanczuk-Seiferth N, Otto K, Schweiger JI, Tost H, Nöthen MM, Rietschel M, Degenhardt F, Witt SH, Meyer-Lindenberg A, Heinz A, Walter H (2018) The influence of MIR137 on white matter fractional anisotropy and cortical surface area in individuals with familial risk for psychosis. Schizophrenia Research 95:190-196. PMID: 28958479

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  101. Weitensteiner V*, Zhang R*, Bungenberg J, Marks M, Gehlen J, Ralser DJ, Hilger AC, Sharma A, Schumacher J, Gembruch U, Merz WM, Becker A, Altmüller J, Thiele H, Herrmann BG, Odermatt B, Ludwig M, Reutter H (2018) Exome sequencing in syndromic brain malformations identifies novel mutations in ACTB, and SLC9A6, and suggests BAZ1A as a new candidate gene. Birth Defects Research 110:587-597. PMID: 29388391. *These authors contributed equally to this work.

  102. Went M, Sud A, Försti A, Halvarsson BM, Weinhold N, Kimber S, van Duin M, Thorleifsson G, Holroyd A, Johnson DC, Li N, Orlando G, Law PJ, Ali M, Chen B, Mitchell JS, Gudbjartsson DF, Kuiper R, Stephens OW, Bertsch U, Broderick P, Campo C, Bandapalli OR, Einsele H, Gregory WA, Gullberg U, Hillengass J, Hoffmann P, Jackson GH, Jöckel KH, Johnsson E, Kristinsson SY, Mellqvist UH, Nahi H, Easton D, Pharoah P, Dunning A, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N, Nickel J, Nöthen MM, Rafnar T, Ross FM, da Silva Filho MI, Thomsen H, Turesson I, Vangsted A, Andersen NF, Waage A, Walker BA, Wihlborg AK, Broyl A, Davies FE, Thorsteinsdottir U, Langer C, Hansson M, Goldschmidt H, Kaiser M, Sonneveld P, Stefansson K, Morgan GJ, Hemminki K, Nilsson B, Houlston RS; PRACTICAL consortium (2018) Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. Nature Communications 9(1):3707. doi: 10.1038/s41467-018-04989-w. Erratum in: Nat Commun. 2019 Jan 10;10(1):213. PMID:  30213928

  103. Went M, Sud A, Speedy H, Sunter NJ, Försti A, Law PJ, Johnson DC, Mirabella F, Holroyd A, Li N, Orlando G, Weinhold N, van Duin M, Chen B, Mitchell JS, Mansouri L, Juliusson G, Smedby KE, Jayne S, Majid A, Dearden C, Allsup DJ, Bailey JR, Pratt G, Pepper C, Fegan C, Rosenquist R, Kuiper R, Stephens OW, Bertsch U, Broderick P, Einsele H, Gregory WM, Hillengass J, Hoffmann P, Jackson GH, Jöckel KH, Nickel J, Nöthen MM, da Silva Filho MI, Thomsen H, Walker BA, Broyl A, Davies FE, Hansson M, Goldschmidt H, Dyer MJS, Kaiser M, Sonneveld P, Morgan GJ, Hemminki K, Nilsson B, Catovsky D, Allan JM, Houlston RS (2018) Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology. Blood Cancer Journal 9:1. doi: 10.1038/s41408-018-0162-8. PMID: 30602759

  104. Witt SH, Frank J, Gilles M, Lang M, Treutlein J, Streit F, Wolf IAC, Peus V, Scharnholz B, Send TS, Heilmann-Heimbach S, Sivalingam S, Dukal H, Strohmaier J, Sütterlin M, Arloth J, Laucht M, Nöthen MM, Deuschle M, Rietschel M (2018) Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation. BMC Genomics 19(1):290. doi: 10.1186/s12864-018-4652-7. PMID: 29695247  

  105. Wray NR, Ripke S, Mattheisen M, Trzaskowski M, … Degenhardt F, …, Forstner AJ, …, Herms S, …, Hoffmann P, … Cichon S, …, Li QS, …, Nöthen MM; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium [Forstner AJ, Herms S, Hoffmann P, Cichon S, Nöthen MM, Maaser A, Schumacher J, Reif A] (2018) Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics 50:668-681. PMID: 29700475

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