The elective module „Neurogenetics“ (WPM 12) takes place during the Neuroscience course. It is held in the summer term and in time-group 2.
- 4 weeks full-time from 9:00 – 17:00 (lecture, seminar, practical)
- Course–rooms in the Biomedical Center (BMZ); Institute of Medical Biometry, Informatics, and Epidemiology (IMBIE); Dept. of Genomics, Life & Brain Center; and the Neurocenter – room assignments will be announced at short notice
- Requirements for participation: regular attendance, seminar-presentation including handout, protocols for the performance of practicals
- The number of participants is limited to 12
The course describes genetic and epigenetic alterations, and the mechanisms by which these lead to CNS dysfunction (e.g. neurological and psychiatric disease, brain tumor). Students will be introduced to methods used for the systematic investigation of genetic variation, from the level of DNA to the level of chromosomes. They will also learn about gene-based approaches to the treatment of human diseases, and methods used to generate animal models of human disease.
The content of the „Neurogenetics“ module will address the following topics:
- Fundamentals of genetics and an introduction to Neurogenetics
- Genetics of complex neurological and psychiatric diseases
- Genetics of monogenic neurological diseases
- Epigenetics and mitochondrial genetics
- Functional genomics of epilepsy: experimental and therapeutic approaches
All course documentation will be made available to students via the eCampus.
1. Kandel, Schwartz, Jessel, Principles of Neural Sciences, McGraw Hill
2. Strachan, Read, Human Molecular Genetics, Garland Science
3. Thomas, Statistical Methods in Genetic Epidemiology, Oxford University Press
4. Pitkänen, Schwartzkroin, Moshe, Models of Seizures and Epilepsy, Academic Press